The Dean Lab at UTSW

The Dean Lab is a multi-disciplinary team of biologists, chemists, physicists, and engineers at the University of Texas Southwestern Medical Center in Dallas, Texas. We develop advanced microscopy technologies to study cellular signaling processes in complex tissue contexts. Our goal is to understand how cells make decisions in the context of their native environment, and how these decisions go awry in disease. More information about our research can be found on our website.

Research Projects

  • navigate - Light-sheet microscopy software packages for intelligent imaging of complex tissue samples. navigate is equipped with a series of plugins that extend its functionality, enabling the use of robotics, imaging cells in a projection format, accessing additional hardware, and leveraging real-time feedback from ilastik. To enable users to generate their own plugins, we provide a plugin template.

  • Altair - A series of cost-effective, easy-to-assemble, and performant light-sheet microscopes for interrogating cells and tissues at the highest resolution.

Educational Resources

  • CI2023 - An introduction to continuous integration and continuous deployment for scientific software.

Publication Repositories

For many manuscripts published over the years, we provide access to CAD files, software, and data via GitHub. These repositories are organized by publication year. You can find this information Publication Repositories.

Our Supporters

The Dean Lab is supported by the following funding sources:

Repositories